Sentence examples for reference concordance from inspiring English sources

We will refer to this concept as "reference concordance" and in the results we will discuss how reference concordance was used to validate the reproducibility of cDNA array data from which putative candidate endogenous reference genes were identified.

In this fashion a pool of genes expressed with high level of reference concordance was selected.

Confidence about array quality was based on the principle of reference concordance as previously described [ 22].

The following steps were pursued: 1) Reproducibility assessment of the data set through determination of reference concordance.

First, the seven experiments used for the analysis of reference concordance in which labeling was done identically to the rest of the experimental samples (test labeled with Cy5 and reference with Cy3) were used to calculate experimental variance (Table 1).

We studied 384 of 419 consecutive array experiments remaining after the exclusion of the 14 reference concordance experiments and 21 experiments judged of poor quality due to missing data or irregular distribution by M-A plot analysis.

SNV: Single nucleotide variant; WES: Whole exome sequencing; WGS: Whole genome sequencing; GAP: Genome analysis pipeline; RM: Reference material; Concordance: Genotype concordance; NRS: Non-reference sensitivity; NRC: Non-reference concordance; GIAB: Genome in a bottle.

Furthermore, the percentage of variants that had high values (>0.9) for another three measures (non-reference sensitivity, non-reference genotype concordance and precision) were 90 (88, 75) for GATK (SAMtools, freebayes).

Non-reference (NR) concordance, that is concordance only at heterozygous or non-reference homozygous genotypes, was calculated using GATK [ 24, 25] and concordance exceeded 98% for all individuals genotyped.

Over 99.8% of sequencing reads mapped to the reference sequence with concordance to the genome annotation.

For the HLA region, using the HapMap reference panel the concordance rate was 99.35% and the proportion of non-missing genotypes 97.4%, and with the 1000 Genomes reference panel the concordance rate was 99.5% and the proportion of non-missing genotypes 99.05%.