Sensitivity, specificity, negative predictive value, and positive predictive value of the NEECHAM scale refer to the CAM-ICU as the reference assessment tool [ 15, 16].
(2010), that collects 54 indicators and 99 metrics and is the only reference assessment found for the case of Vancouver.
All these cases were in stage I according to the reference assessment.
Ingrid Hauser, Electron Microscopy Unit, Department of Dermatology, University of Heidelberg, for reference assessment of the skin biopsy.
Only in three cases, all in stage I according to the reference group (cases 3, 4 and 5), did the assessors mostly disagree with the reference assessment, whereas in general, the agreement with the reference assessment was 65%.
The agreement with the reference assessment was highest in the most severely affected cases (Braak stage VI-96VI-96% lowest in the mildly affected cases (Braak stage I-33I-33%verall 59%.
There was 81% agreement with respect to the reference assessment for the isocortical Braak stages (V VI), 68% for the limbic stages (III IV) and 43% with respect to the entorhinal stages (I II).
The agreement with the reference assessment was 91% for the isocortical stages (V VI), 72% for the limbic stages (III IV) and 50% for the entorhinal stages (I II).
Among patients who were HER2 positive by local assessment and, after the early protocol amendment, by either central or reference assessment, overall concordance was high among the pairs of HER2 measures: 87.6 % between central IHC and RT-PCR, 84.4 % between central FISH and RT-PCR, and 85.8 % between central IHC and central FISH.
It has normative value referenced assessments, with means of 100 and Standard Deviation (SD) of 15 points.
