Sentence examples for reference agent from inspiring English sources
Most of these compounds displayed good activities against Gram-positive organisms comparable to reference agent LBM-415.
The broth microdilution microtiter plate (MTP) method with twofold dilution of the compounds, or ciprofloxacin (reference agent) in 96-well polystyrene microplates, was used.
More recently, gemcitabine has become the reference agent for these neoplasias because of the histologically common origin of biliary cancer and exocrine pancreatic cancer.
Although the tested compounds did not carry a sulfonamide group, an important pharmacophore for CA inhibitory activity, it was a remarkable finding that most of them were more effective on hCAs than acetazolamide (AAZ), the reference agent.
Moxifloxacin is the most widely used positive reference agent in clinical cardiac repolarization studies, but it has not been characterized in common marmosets which are uniquely suited to studies in early-stage development due to their small size and minimal test article requirements.
The effects of all isolated compounds at concentration of 10 µM, and a reference agent, meloxicam (20 µM) were further examined on LPS-induced COX-2 protein, mRNA expression and LPS-induced PGE2 production in RAW 246.7 cells by reported method with slight modification.
Many 7-monoarylaminomethyl derivatives exhibited high potency against Gram-positive organisms compared to reference agents: vancomycin and pazufloxacin.
Two reference agents, R- Deprenyl and MK-801, known to alter the concentration of MPP+ in MPTP treated mice were evaluated.
For both reference agents and biosimilars, rare adverse events and long-term efficacy and safety can only be assessed through post marketing surveillance; therefore, particular emphasis should be placed on the traceability of these agents in clinical practice.
To demonstrate that the developed method can be applied to monitoring changes in ACh concentrations in vivo, reference agents that have previously been shown to influence ACh levels were studied in rat dorsal hippocampus.
Compound 15b (4- benzylamino quinazolin-2-ol) was the most potent Aβ aggregation inhibitor (Aβ4- benzylamino quinazolin-2-olnd 1.4- benzylamino quinazolin-2-ol the reference agents curcumin and resveratrol.
