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However, the naturally occurring biomolecules are typically reengineered into forms that are more facile, economical, efficacious, or robust.
4D11 and 9H4 were reengineered into antibody fragments [variable region fragment (Fv) and single-chain Fv (scFv)] and were validated as suitable models for their full-sized IgG counterparts by surface plasmon resonance and isothermal titration calorimetry.
The coextrusion process allows the carbide and metal binder phases to be reengineered into specific locations at a mesoscale level (10's to 100's of microns), resulting in a functionally designed cellular (FDC) architecture.
ISICS, originally a C language program for calculating K-, L- and M-shell ionization and X-ray production cross sections from ECPSSR and PWBA theory, has been reengineered into a C++ language class, named ISICSoo.
Subsequently, this proof-of-principle compound, termed vasculotide (VT), was reengineered into a more pharmaceutically amenable preparation that excludes the avidin/biotin complex in favor of a tetrameric polyethylene glycol (PEG) scaffold (Additional file 1).
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The reengineered channel inserted into a lipid membrane exhibits robust electrophysiological properties ideal for precise sensing and fingerprinting of dsDNA at the single-molecule level.
In the primary tumor site, reengineered cancer cells transform into an invasive phenotype to penetrate the tumor stroma and enter the blood circulation or lymphatic system via intravasation.
The reengineered plasmid vectors were introduced into Bacillus anthracis Sterne by electroporation and selection on erythromycin plates.
In addition, PylRS tolerated propionyl- and butyryllysine, providing access to H3 with the corresponding residues at position 9. Direct incorporation of methyllysine residues into proteins through reengineered aaRSs has so far been unsuccessful.
As Linear Tech and Altera management make clear, most of the installed base of industrial equipment is being recast, reengineered and redeployed, integrating individual networked identities into once totally stand-alone items.
Upon contact with a mammalian cell, these reengineered E. coli deliver target protein(s) into the host cell cytoplasm.
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