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We are stuck in a redundant loop, now.
Redundant loop formation by Schwann cells and collapsing myelin that form ovoid, flat axons could contribute to axonal necrosis [50].
However, redundant loop formation is characteristic for dy/dy mice [48], and we also found many axons with redundant loops (Fig. 11H, and top panel overview).
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He added, "There are so many redundant loops that something else may take over to restore the fat that people want to lose".
The old tunnels had run in a straight line from the reservoirs into the city, but City Tunnel No. 3 was designed with various redundant loops (upper Manhattan has a loop; Brooklyn and Queens have a loop) that would pass through the chamber, so that parts of the city can be taken off-line without cutting the water supply entirely.
Severe axonal atrophy went along with paranodal myelin sheath instability indicated by redundant loops and tomacula (Figure 1I).
The post-myelination pathologies leading to axonal degeneration (Fig. 11A E) included: myelin degradation, axon demyelination (B,C), myelin intrusions (A), excessive myelin outfoldings (A,D) and redundant loops (H).
This resulted in a dataset of 130 non-redundant loops (Table 3).
The small value of cost1 ij in (1) prevents redundant flow-loops and does not affect the result.
The predominant irregular features were myelin outfoldings and infoldings of various complexities, in combination with redundant myelin loops, both around nodes of Ranvier and along internodes.
Recessive mutations in SBF2 are typically found in patients with redundant myelin loops or myelin outfoldings in sural nerve biopsies [8].
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