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Given the proven utility of the genetic macrophage ablation model in this study, the creation of a similar mpo- and/or lyzC-driven ablation fish would more conclusively clarify the supportive or reductive role of neutrophils in various regenerative contexts.
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Tyr has been demonstrated to perform both reductive and oxidative roles in relation to inorganic metal cofactors bound in proteins.
NADPH plays a key role in reductive biosynthesis and cellular defense against oxidative damage [80].
These steric effects do not play a role in reductive elimination from LPdMe2.
Second, the growth and decay of biomass from soluble carbohydrate plays a significant role in reductive dehalogenation.
Recovery of sequences affiliated with phylogenetic groups containing known anaerobic-halorespiring organisms such as Desulfitobacterium, Dehalobacter, and certain groups of iron reducers provided qualitative support for a role of reductive dechlorination processes in the aquifer.
The objective of this study was to examine the role of reductive activation of DOX by the human liver CPR in increasing its cytotoxic activity especially in regard to MDR tumour cells.
The aim of this study was to examine the role of reductive activation of DOX by the human liver NADPH cytochrome P450 reductase (CPR) in increasing its cytotoxic activity especially in regard to MDR tumour cells.
In some cases, C-terminal reductase domains are found in place of TEI, and their role in reductive product release was shown or hypothesized (Gomez-Escribano et al. 2012 and references therein).
In this study, we investigated the role of reductive activation of DOX by the human liver CPR in increasing its cytotoxic activity against human promyelocytic leukaemia cells exhibiting two different phenotypes of MDR related to the overexpression of P-glycoprotein (HL60/VINC) or MRP1 (HL60/DOX).
Most alarming is Andreeva's reductive implication that more roles for "ethnic" actors isn't "fair" to white actors.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com