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There were also parallel reductions in the expression of the enzyme cyclooxygenase-2, which forms pro-inflammatory prostaglandin E2.
Treatment of E18.5 lung explants with exogenous MIA caused significant reductions in the expression of the lung differentiation markers Sftpa, Sftpb, Sftpc, and Abca3.
Microarray analysis showed significant reductions in the expression of Sftpa, Sftpb, Abca3, Aqp5, Lzp-s, Scd2, and Aytl2 in lungs misexpressing MIA.
In addition, reductions in the expression of osteoblast differentiation markers were also partially restored with rapamycin, whilst trends towards an increase in immune-related osteoclastogenic markers CD16b and DAP12 in sick rabbits were reduced with rapamycin.
Zicam-treated MOE showed significant reductions in the expression of above biochemical markers.
There are also considerable reductions in the expression of a number of homeobox genes (HOXB3, 4, IRX, HHEX, HESX1).
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Regarding combined exercise, 50% of studies reported a reduction in the expression of the receptors.
As the result of PEGylation, the NP treatment resulted in the reduction in the expression of most of the genes.
The treatment of osteoarthritic chondrocytes with simvastatin and mevastatin has shown a reduction in the expression of MMP-3 [12] 12].
HIF1-deficient T cells display a marked reduction in the expression of IL-17 and Th17-signature genes.
Furthermore, reduction in the expression of stemness, and invasion related genes was observed in the both cell lines.
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