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The case studies in Kenya and in Ghana also highlighted recent apparent reductions in outflow of nurses and doctors, but this was in part reportedly a result of relative improvements in working conditions in the countries, and was also attributed (in the case of declining flows to the United Kingdom) to tougher entry requirements and a reduction in demand from the United Kingdom.
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Averaged across the RPE under patterned defocused stimulation, a net reduction in outflow could result if the reverse flow probability was thus biased.
Gaasterland and Kupfer (1974) [ 11] applied repeated, circumferential argon laser photocoagulation to the trabecular meshwork in both eyes of each of the five Rhesus monkeys and induced a sustained IOP elevation in seven out of ten eyes by a marked reduction in outflow.
Wastewater samples were collected at the inflow (IN), outflow of VF unit (OUT-VF) and outflow HF unit (OUT-HF).
Such changes could include an increase in episcleral venous pressure, reduction in trabecular outflow facility, or reduction in uveoscleral outflow.
The magnetic flux reduction in the outflow region arises from energy conversion in the diffusion region.
A bumetanide induced reduction in RPE outflow is also a likely cause of the increase in VC depth observed in the bumetanide injected eyes reared with 0D and+10D lenses, given that aqueous humour production and intraocular pressure changes under bumetanide are minimal (at least in mouse and monkey [36], [37]).
Thus, in a second experiment, we tested the idea that if negative lens defocus results in myopia and ocular elongation through a reduction in the outflow of fluid across the RPE, then intravitreal injection of the diuretic bumetanide would restore RPE fluid flow as evidenced by relative suppression of abnormal vitreal chamber growth and inhibition of myopia.
Increase in RV afterload induced by increased lung volume contributes to this reduction in RV outflow.
A reduction in uveoscleral outflow is the likely explanation for the normal IOP despite a reduction in aqueous flow.
The most important risk factor is high intraocular pressure (IOP), due to the reduction in the outflow of aqueous humor through the iridocorneal angle [ 1, 2].
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