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Furthermore, obese adolescents with type 2 diabetes, as well as those with metabolic syndrome, show reductions in cognitive performance and white matter microstructural integrity [ 5].
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As a combined group, PwMS demonstrated a reduction in cognitive performance in 7 (out of 7) cognitive domains, in addition to the global cognitive score.
It was also estimated that a reduction in cognitive performance associated with a 25 dB hearing loss was equivalent to a reduction associated with a 7-year age difference.
The most often reported positive results are improved night-time sleep, reduction in agitation, and improvement in cognitive performance.
It is unclear what determines PGD2's inflammatory status, but our data showing an improvement in cognitive performance and a reduction in the expression levels of pro-inflammatory markers in the AD mice by fisetin suggest that the increased levels of PGD2 and its metabolites might be associated with the anti-inflammatory action of fisetin in the brain.
Interestingly, the improvement in cognitive performance was associated with a reduction in insulin resistance, suggesting a possible influential role of glucose metabolism in modulating cognitive function.
In addition, Burgess et al. demonstrated a plaque reduction that effectively reached 20% and showed an associated improvement in cognitive performance in the Y maze test6.
However, this reduction in amyloid content has not been conclusively associated with improvements in cognitive performance or a slowing in the progression of AD [ 2, 3].
Cognitive Remediation Therapy (CRT) has demonstrated consistent effect in cognitive performance, symptoms and psychosocial functioning.
Results revealed no significant group difference in cognitive performance between COMT genotypes in any of the 19 cognitive measures.
The group that did stretching and toning displayed no significant change in cognitive performance over time.
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