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The starting dose of sagopilone was 16 mg/m, and dose reductions in case of ≥ grade 3 toxicity to 12 and 9 mg/m were prespecified.
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Across all sites, no significant reductions in cases of stroke are estimated.
The development of these individual prophylactics resulted in significant reductions in cases of and deaths from the respective diseases.
This has resulted in increased demand for demonstration of the health benefits projected for environmental regulations, such as reductions in cases of disease (such as asthma) associated with reductions in air pollution (U.S. EPA 2003b).
23 Previous reviews have generally concluded that reductions in the frequency of injection and sharing of injecting equipment that are associated with exposure to opiate substitution treatment translate into reductions in cases of HIV infection.
A previous Cochrane systematic review concluded that "available data are limited but it appears that the reductions in risk behaviour related to drug use do translate into actual reductions in cases of HIV infection".
The dose reduction in case of renal failure was statistically significant (Table 2).
For morphological characterization of NPs, TEM images as in Figs. 3 and 4 were obtained which shows clear distinction of particle size reduction in case of surfactant used.
The much lower reduction in case of sugarcane bagasse seemed significant when the cost of these two carbon sources was compared.
Also when both uniform spaced and optimal spaced predistorters were implemented using VHDL synthesis, the gate count has shown almost two times reduction in case of optimally spaced compander.
Time-course studies over a 2-month period indicate that immobilization through the sodium silicate process led to a reduction in activity of ∼5% as compared to ∼30% activity reduction in case of free cells in buffer indicating that immobilization leads to stabilization, a key parameter in biosensor development.
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