Other negative effects of high fluoride in groundwater include reduction of intelligent quotient and kidney damage.
These high F− values have the potential of causing serious health problems such as kidney failure, dental and skeletal fluorosis, reproductive problem and reduction in intelligent quotient of consumers.
Lead and polychlorinated biphenyls (PCBs) both cause a reduction of intelligence quotient and behavioral abnormalities in exposed children that have features in common with attention deficit hyperactivity disorder.
Because LTP is thought to be correlated with learning ability, these observations may provide at least a partial mechanism to explain the reduction of intelligence quotient observed in humans exposed to PCBs early in development.
In both cases, we found a dramatic (four- to seven-fold) reduction in lordosis quotient (number of lordosis stances in response to male mounts) in cGαo-/ mice versus B6, cGαo+/-, and Gαofx/fx controls (t-test: P <0.05 (B6 males); ANOVA: F3,44 = 5.05; LSD: P <0.01 (BALB/c males) ).
First, this is supported by a reduction in the respiratory quotient.
I have pointed out (Weiss 1988) that even a 5-point (5%) reduction in mean intelligence quotient in a population of 100 million increases the number of individuals classified as retarded from 6 million to 9.4 million.
Our study expands the existing but very limited literature base on the effect of As on the intellectual function of children, and reports a measurable reduction of IQ (intelligence quotient) scores due to As exposure.
In a human trial, treatment with 12 mg taranabant resulted in a significant increase in resting energy expenditure, most likely due to an increase in the fat oxidation rate, supported by a reduction in the respiratory quotient when taking the drug (77).
Reduction in the resting respiratory quotient and, therefore, greater metabolic efficiency in consuming fats.
