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First, we dropped, the cost reduction question and the market share question due to low internal consistency, measured by Cronbach's alpha.
A detailed process of item generation, item reduction, question formatting, and pretesting or piloting of the questionnaire was completed [ 10].
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While a previous study exists evaluating rotator cuff insertions for tuberosity reduction, questions can be raised about its reproducibility [3].
Instead of materialism versus vitalism (ontological reduction questions), the explanatory conflict involved the nature of differentiation in early ontogeny and to what degree it is prespecified.
In this study, using the responses from the risk reduction questions results in willingness-to-pay estimates orders of magnitude higher than when respondents directly valued the prevention of one case of either event.
For subjects with DPN, Celliant™ subjects reported more pain reduction in question Ia (0.22 vs. 0.19, p = 0.978), whereas controls reported more reduction in pain for questions Ib (0.06 vs. -0.01, p = 0.566), and Ia+b (0.45 vs. 0.21, p = 0.587).
In all the recent debate about cuts and deficit reduction, one question that should perhaps be asked more is: dude, where's the opposition?
Steps for developing a PRO instrument involve item generation, item reduction and question formatting.
The methodological approach used in the pre-validation development of new instruments (item generation, item reduction and question formatting) should be robust and transparent.
A three-class classification can be expected to have more uncertainty than the two-class classification scheme, producing a higher error rate and a smaller reduction in question count.
However, here again a word of caution is warranted: for any kind of reduction, the question is of course how far can one reduce a complex biological process, without losing characteristic features?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com