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Measurement of carotid IMT is being employed increasingly frequently in clinical trials to assess the harmful effects of risk factors on vessel walls as well as the effect of treating risk factors that cause a reduction or prevent progression of IMT [ 7, 20].
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Treatment is lengthy and has severe side effects, which may lead to dose reduction or even prevent treatment completion.
This suggests that the presence of pharmacies alone may not guarantee sufficient access to syringes for IDUs to accomplish a reduction in injection risks or prevent HIV transmission.
A continuous treatment and training to increase oxygen uptake, improve balance and strength, maintain joint ROM, and reduce pain throughout adolescence may further improve walking performance or prevent a reduction in walking ability.
Initially, we used dominant-negative (kinase-dead) GRK mutants to disrupt ETAR/GRK isoenzyme-specific interactions in an attempt to attenuate or prevent the reduction in ETAR responsiveness observed on re-addition of ET-1.
Since GRK proteins are known to regulate the signalling of other PLC-coupled GPCRs expressed in MSMCs, we initially utilized dominant-negative (kinase-dead) GRK mutants to disrupt P2Y2-receptor/GRK isoenzyme-specific interactions in an attempt to attenuate or prevent the reduction in receptor responsiveness observed on re-addition of UTP subsequent to a desensitizing pulse of this agonist.
Because arterial stiffness is involved in the development of diabetes complications, debating if PWV reduction may prevent or even counteract progression of diabetes complications is warranted.
The LPV anti-windup scheme is combined with an LPV controller that shifts its focus from a "soft" setting to a "stiff" setting depending on the need for acceleration minimization or relative displacement reduction to prevent bumping.
The Diabetes Prevention Program DPPP) has demonstrated that an intensive lifestyle intervention focused on lifestyle changes and weight reduction can successfully prevent or delay the onset of type 2 diabetes and the metabolic syndrome in overweight or obese adults with pre-diabetes [ 6].
Methods and results of this study may help to allocate surveillance and other risk reduction measures to prevent or minimize the potential impact of ASF introduction into the EU.
However, there is no available evidence from clinical trials that a reduction in CRP directly reduces or prevents further CVD events.
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