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This resulted in a prominent reduction of repeat sequences (up to 40%) and an enrichment of coding sequences (up to 60%).
If patients have followed an uneventful hospitalisation period, they can be imaged subsequently with CEUS [34], leading to the reduction of repeat CT scans, especially in young ages [33].
Thus, the largest chicken chromosomes, like the rest of the chicken genome, showed a pattern indicating adaptive reduction of repeat array length.
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The rescued behavior was not due to a reduction of repeat-containing RNA in alg-2 null animals, as the levels of mRNA produced from the expanded repeat were the same in each strain (Fig. 7C).
While unequal crossover among repeat sequences can lead to an increase of copy numbers, the alternative outcome is a reduction of repeats.
Better recall of root morphology, established coronal access and reduction of repeated procedures such as application of rubber dam isolation and local anaesthetic allow dentists to shorten the total chairside time.
This finding is consistent with the hypothesis of Burt [ 10] that the reduction of repeating DNA in avian genomes is adaptive in permitting chiasma formation and alignment of microchromosomes.
Such repeats can be collectively considered as one entity of domain; in instances of insertion/deletions of some of the repeats but not all, we annotate the change as Insertion/Deletion – Reduction of repeats; and when all the repeats are involved, we annotate the change as Insertion/Deletion – All repeats.
A pilot randomised trial of developmental group psychotherapy compared with routine care in 63 adolescents referred with repeated self harm to child and adolescent mental health services 25 showed a significant relative reduction of repeated self harm over 29 weeks of follow-up (2/31 in developmental group psychotherapy versus 10/31 in routine care; odds ratio 6.3; 95% CI 1.4 to 28.7).
In either case, the evidence for numerous, independent events of elimination of long arrays implies that reduction of DNA repeat length and thus of overall genome size in birds has occurred as a result of adaptive evolution.
This strongly suggests that there was selective pressure within the mammalian lineage that resulted in the reduction of Xin repeats.
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