Sentence examples for reduction of relapse from inspiring English sources

The distinct binding kinetics of the four anti-PD-L1 MAbs may differ in MAb-driven off-target escape, and thereafter duration of anti-tumor efficacy and reduction of relapse.

Natalizumab, a recently re-approved drug for MS treatment, has been shown to reduce the numbers of CD19+ B cells and CD138+ plasma cells within the CSF [32] which correlated with the reduction of relapse rates as well as of the inflammatory disease activity on MRI.

Similarly, luminal B BCIRG001 patients showed a 44% reduction of relapse risk with docetaxel [ 29].

In recent studies, data indicates that the addition of rituximab to CT implies a substantial reduction of relapse with rates ranging from 20 to 35%% [ 8, 21, 24].

Patients randomized to receive reintroduction had an estimated reduction of relapse of 14% whether the initial chemotherapy consisted of three cycles or six cycles.

First, in several types of NHL, chemotherapy has become the primary modality with radiotherapy used for consolidation and reduction of relapse risk.

Psychological support together with prophylaxis therapy with OnabotulinumtoxinA produced in patients a reduction of relapses in drug abuse of 38% compared to a sample of 108 patients age and gender matched that was not eligible for psychological support but received the detoxification and prophylaxis therapy.

In acute myeloid leukemia (AML) blasts, hERG K+ channel expression is associated with a 50% reduction of relapse-free and overall survival time compared with patients with hERG-negative AML (12 versus 23 months).

When we focused on patients treated with chemotherapy, we observed a highly significant reduction of relapse-free survival independent from the tumor subtype (p < 0.01, HR 1.91) in ER− patients (p < 0.01, HR 2.97) and in ER−/PR− patients (p < 0.01, HR 3.08) among patients expressing high levels of ST3GAL2 (Fig.  7b).

Such a result if validated – would support the assumption that reduction of relapses slows down the accumulation of disability.

So far, results show a reduction of relapses and magnetic resonance imaging (MRI) activity in patients with relapsing remitting MS (RRMS), which was associated with a significant reduction of sustained disability progression in one of the two phase III trials.