Sentence examples for reduction in the dose from inspiring English sources
In this case, the induction of acetaminophen and oxycodone required a reduction in the dose of warfarin.
Calculation of dose reduction index (DRI) indicated that at 50 90% growth inhibition level, the combination of the drugs caused 3.6 5.8- and 4.1 11.5-fold reduction in the dose of CdA and 4.1 11.5-fold >1000-fold reduction in the dose of AZT in H9 and H9-araCdAells, respectively.
More importantly, it can provide durable remission for patients who have a suboptimal response to prior single-agent melphalan conditioning for ASCT, without requiring a reduction in the dose of melphalan.
The results showed that the co-injection of the SVCV DNA vaccine and the molecular adjuvant allowed (i) a ten-fold reduction in the dose of pAE6-Gsvcv without compromising its efficacy (ii) an increase in the duration of protection, and (iii) an increase in the survival rate.
Reduction in the dose of proapoptotic genes hid, rpr and grim (Df 3L 4W) dominantly suppressed a mblC overexpression phenotype.
Consistent with this hypothesis, a reduction in the dose of the stat92E gene affects both cell cycle phasing and cell size in ept/M 3) tumors (see accompanying paper by Gilbert et al).
Other recommendations point in the same direction, notably from the HAS in 2012, whereby a reduction in the doses by half is proposed in case of renal impairment and creatinine clearance below 30 mL/min [12].
In the first, we compared conventional and conformal radiotherapy (CFRT) at a standard dose of 64 Gy (Dearnaley et al, 1999) and showed a significant reduction in the dose-limiting late side effect of proctitis using CFRT.
Their safety has been improved over the years with the reduction in the doses of estrogen and progestogen.
These findings could be the result of a reduction in the dosing of irinotecan in UGT1A1*28 carriers and/or homozygous (because of the appearance of severe diarrhoea).
A reduction in the doses of methotrexate and steroids was allowed after patients had received at least 3 months of etanercept in addition to methotrexate.
