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Ronald L. Friedman, superintendent of Great Neck schools and president of the Nassau County Council of School Superintendents, said the reduction in STAR reimbursements came as a surprise to education officials.
The effect on StAR is seen at the transcriptional level, with a significant reduction in STAR mRNA levels in AAAS-knockdown cells [0.47 ± 0.01 (mRNA levels relative to GAPDH)] compared with controls (0.62 ± 0.04) (P <.01, n = 3).
Specific mitochondrial antioxidant mechanisms exist in the adrenal cortex, and when the antioxidant capacity is exceeded, there is an accumulation of H2O2 in the mitochondria with overflow into the cytosol that triggers a reduction in StAR expression (34).
We hypothesize that ALADIN deficiency leads to an imbalance in cellular redox homeostasis, resulting in a reduction in StAR and P450c11β and consequent impairment of cortisol and in approximately 15% cases, mineralocorticoid production (1).
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Although several studies in Leydig cells demonstrate a clear reduction in 30-kDa StAR protein expression in response to ROS, it is unclear whether there is also an effect of ROS at a transcriptional level because current data are inconsistent (31, 32).
As we find negligible contamination of the companion with ejecta material, the difference in evolution is effectively due to the reduction in mass of the star.
In Leydig cells, oxidative stress inhibits the mitochondrial import and processing of StAR with a reduction in the 30-kDa intramitochondrial form of StAR, resulting in a reduction in steroidogenesis (31).
As non-fusing helium ash accumulates in the core of a main-sequence star, the reduction in the abundance of hydrogen per unit mass results in a gradual lowering of the fusion rate within that mass.
Mr Dorman also welcomes the reduction in one- and two-star generals, respectively from 26 to 18 and from ten to six, resulting from the merger of two commands.There is most scepticism about the enhanced role of the reserve, which is to expand to an active pool of 30,000.
The gas and dust between the Sun and HDE 226868 results in a reduction in the apparent magnitude of the star as well as a reddening of the hue red light can more effectively penetrate the dust in the interstellar medium.
After immunoblot and densitometric analysis, we observed a significant reduction in the expression of 30 kDa StAR protein relative to GAPDH in AAAS-knockdown H295R cells compared with controls (P <.01, n = 4).
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