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Use of a pre-intervention and post-intervention study design meant that the interviewer could not be blinded to group allocation and that factors other than the IRCMAC could have contributed to the reduction in medication administration errors and locum medical service attendances over time.
The mean reduction in medication was 50%.
This may lead to reduction in medication intake days and lower headache-related disability as a consequence.
Tohmeh et al. [14] showed there was a significant reduction in medication usage from baseline to last follow-up.
Of these, 119 patients reported a reduction in acute medication use, averaging (8.5 ± 7.7) days reduction in medication use.
In a systematic review by Manias et al., medication reconciliation at ICU admission was one of the four interventions demonstrating a reduction in medication errors [16].
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At a median follow-up of 12 months, the Authors observed a meaningful improvement of the headache in all the implanted patients, allowing reduction in medications intake.
Despite observed improvements in prescribing appropriateness, it is unclear if the identified interventions resulted in clinically significant improvements, for example, reduction in medication-related problems.
The Australian study reported a significant reduction in medication-related problems after intervention by the pharmacists, and a significant improvement of adherence to the medication regimen [ 16].
In addition, a recent study using this same dataset showed a reduction in medications for conditions expected to improve after bariatric surgery but no change in other medication classes for disorders less likely to be affected by surgery, such as thyroid or allergy prescriptions.
Three studies showed significant reductions in medication costs; five other studies could not support this.
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