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We found that deletion of ybbO gene, which encodes NADP+ dependent aldehyde reductase, led to >90% reduction in long chain fatty alcohol production.
In addition to decrease of bone mass, Slc39a13-KO mice had a significant reduction in long bone length (Figure S4A).
A major finding in our study was the reduction in long term viability of human and mouse neurons deficient in PINK1.
In a community cohort study of 3,681 patients with pneumonia [18], Myles and colleagues observed that current statin use was associated with a 67% reduction in 30 day mortality (adjusted hazard ratio 0.33, 95%CI 0.19 0.58), and a 55% reduction in long term mortality (adjusted hazard ratio 0.45, 95%CI 0.32 0.62).
Our morphometric analysis showed a reduction in long bone weight and, in the case of the tibia, a reduction in length in Mecp2stop/y mice.
10.7554/eLife.09460.011 Figure 5. Reduced magnitude of hippocampal tCREB expression with a corresponding reduction in long term potentiation (LTP) in misaligned mice.
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This reduction in long-term rates might spur aggregate demand.
What if it also made a significant reduction in long-stay hospital use?
And a less vibrant and agile civil society signals a reduction in long-term development for the many.
This greater supply of capital led to a reduction in long-term interest rates and in the cost of capital to businesses and households.
Christopher Frenze, the committee executive director, said the declining average tax rate for the top 1percentt reflected the booming stock market, and the reduction in long-term capital gains tax rates that began in 1997.
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