Importantly, the reduction in hazard of injury by experience persisted even after adjustment for age.
Our study revealed IPT use has contributed to a higher reduction in hazard of acquiring tuberculosis than non-IPT use.
Surprisingly, being in a high demand department was consistently associated with a reduction in hazard of acute injury in this subset of plants.
In time-constant models for TC and BP, antimalarial use during the course of SLE was associated with a remarkable 50%to59%9% reduction in hazard of a CAD event.
Based on the current study findings, an increase in level of total daily physical activity from 2.5 × 10 counts/day to 3.0 × 10 counts/day (50th percentile) could potentially result in a 14% reduction in hazard of developing ADL disability.
The results are confirmed when another SES variable, asset score, has been used as an alternative but greater effect estimate (reduction in hazard of child death), HR 0.26 vs. HR 0.31, was achieved by using our main stratifying variable, maternal schooling.
In view of this the findings concerning absolute reductions in hazard of relapse with increasing frequency of daily home practice should be interpreted cautiously.
The trial was designed to have 90% power to detect a hazard ratio of 0.70, a 30% reduction in hazard rate of death from a hazard rate of 0.6 in the phase III trial at an α level of 0.1 (one-sided).
Using a conservative estimate, our study had 80% power to detect a reduction in hazard ratio of 32% (based upon N = 124 per group, medians of 8 and 10 years, type 1 error = 5% and Bonferroni correction).
In addition, relative to no-goal achievers, both groups of single-goal achievers had significant reductions in hazard for all categories of complications and surgical procedures, except microvascular complications among LDL-C achievers.
