Sentence examples for reduction in differentiation from inspiring English sources

Similarly, overexpression of TET2 or TET3 also leads to a remarkable reduction in differentiation rates (TET2 overexpression: 17.1%; TET3 overexpression: 13.7%) (Fig. 3B).

During the first two steps of lyophilization, there was not a significant reduction in differentiation and clonogenic potential of HPC loaded with trehalose.

Mutation in Cdc27 (causedL71123) caused a modest reduction in differentiation and no visible change in growth.

Thus, the reduction in differentiation observed in some mdx animals is most simply explained as a reduced rate of differentiation.

Several molecular pathways underlying GC-induced reduction in differentiation potential have been identified, such as Wnt/ β-catenin and bone morphogenetic protein 2 (BMP-2) signaling [ 14, 15].

Cells grown in control antibody showed the previously described reduction in differentiation on type I collagen, whereas the addition of Ak7 partially abrogated this effect.

Analysis of the cross-linked proteome in these mice reveals a reduction in differentiation-associated type I and type II cutaneous keratins (Krt1, Krt2, etc).

Neurite outgrowth was not significantly altered in SH-SY5Y cells, but the neuronal differentiation markers indicated a reduction in neuronal differentiation induction after nanoparticle exposure.

Finally, we determined whether the reduction in osteoblast differentiation was associated with changes in the expression of markers of osteoblast differentiation at the mRNA level (Figure 2E).

These data suggest a decrease in ICOS expression on ICOS+/− T cells resulted in a proportional reduction in Th2 differentiation and airway inflammation.

Therefore it is likely that the reduced expression of SMC specific genes and proteins in SM-Dicer KO mice in vivo reflects a general reduction in SMC differentiation and not a loss of smooth muscle cells per se.