Sentence examples for reduction in copy from inspiring English sources

For example, this is striking for the expression of chromosome 6 genes in type A tumors, that have a reduction in expression equivalent to the reduction in copy number.

For LOH to occur, measured as a reduction in copy number, physical loss is required.

Haploinsufficient (HI) genes are those for which a reduction in copy number in a diploid from two to one results in significantly reduced fitness.

Growth remained relatively constant at this increased rate upon further reduction in copy number, and viability remained comparable to the WT in all cases (Additional file 1).

For SWE1, reduction in copy number from four (WT level) to three, resulted in an approximately 18% increase in growth rate.

Reduction in copy number of BLT2 may merely allow the LTB4 to signal through the BLT1, which have higher affinity for the ligand.

Supplementation with NDSF resulted in an increase in 16S rDNA copies of Ruminococcus flavefaciens and a reduction in copies of Ruminococcus albus.

Further reductions in copy number result in increasing numbers of cells with a G2 DNA content.

The other concentrations caused significant reductions in copy numbers as compared to the virus-infected cells.

Some genomes appear to have whole-chromosome amplifications: chromosome I in AWRI796, chromosome III in Foster's O and chromosomes II, V and XV in Foster's B. Several partial chromosomal CNV amplifications hundreds of kilobases long were also identified, as were some reductions in copy number.

DNA copy number profiling revealed remarkable reduction in the copy numbers of CDKN2A, PTEN and TOP2A in HMEC spheres cultured in presence of OPG (Fig.  10e).