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We hypothesized that the reduction in breadth of CD8+ve T cell responses might result in, and therefore correlate with, a decline in selection pressure, particularly in Gag in light of the relative shift away from Gag targeting.
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He said: "Many people did not value the fact that demand had reduced and this has had the effect of creating headroom for a reduction in the breadth of the service.
I attempt to avoid this ambiguity and for this paper define specialization to be a reduction in niche breadth associated with adaptation to any particular environment.
Antagonistic pleiotropy was previously found to be the primary cause of resource specialization and niche breadth reduction in the digital life software platform Avida [ 29], in which self-replicating computer programs evolve.
This definition is close to that used in investigations of niche breadth reduction in Avida [ 29], where it is calculated as the proportion of organisms performing each function summed over all functions, rather than taking the mean over all resources, as we do here.
The collection continued to grow in depth and in breadth.
His range is extraordinary, both in breadth and in altitude.
five motorcycles in breadth. in bike traffic measurements.
"People are really interested in breadth," says Prof Bean.
"There's been success in breadth and in depth.
How much data in breadth does it take?
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