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A low tidal volume aids in reducing the ventilator lung injury but it can also result in dependent atelectasis.
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The possibility of further reducing the ventilator-associated lung injury is of utmost importance, with possible implications in terms of reducing death and multiple organ failure in ARDS patients [23].
When the safety screen (Additional file 1: eFigure 1) was not met, the attending physician attempted to reduce the ventilator settings based on his/her clinical judgment.
Blood acidification at the inlet of a membrane lung therefore should be considered a promising technique to reduce the ventilator needs.
We conclude that in our series, the CTSS did not reduce the ventilator-associated pneumonia incidence, nor the exogenous pneumonia.
Alternative methods for reducing the incidence of ventilator acquired pneumonia (VAP) have received some attention of late.
Given the limitations of these diagnostic criteria, the proof of CHX efficacy in reducing the rate of ventilator-associated pneumonia remains elusive.
Improving the quality of oral hygiene is recognised as an important counter measure for reducing the incidence of ventilator-associated pneumonia amongst critically ill patients.
High-frequency oscillatory ventilation, using very small tidal volumes and relatively high end-expiratory lung volumes, provides a safe and effective means of delivering mechanical ventilatory support with the prospect of reducing the development of ventilator-induced lung injury.
In general, a weaning trial involves reducing the work performed by the ventilator while monitoring for evidence of fatigue or altered gas exchange.
Explained in terms of stress and strain, ventilation with moderate/high PEEP and low Vt will reduce both stress (Vt) and strain (higher EELV induced by higher PEEP), thus reducing the risk of superimposed ventilator-associated lung injury.
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