Sentence examples for reducing the specificity of from inspiring English sources

The authors proposed that AV-45 ROI SUVr included local non-specific white matter uptake, reducing the specificity of the findings compared to PiB in patients.

Pretreatment actually slightly increased the number of false positives, reducing the specificity of pretreated smears (92.6% [87.1 96.4]) as compared to direct aurmine smears.

Furthermore, cross-reactions with other mycobacteria are common [ 11, 17], reducing the specificity of both serological and IFN-γ assays.

This crossreactivity could potentially yield false positive results in IHC, thereby reducing the specificity of the test.

For example, significant uptake of fluorine-18-labeled fluorodeoxyglucose (FDG), the most widely used oncologic PET tracer, occurs in non-malignant inflammatory cells, such as macrophages and neutrophils, reducing the specificity of FDG PET for malignant disease.

Four sequences could not be accommodated without greatly reducing the specificity of the pattern, that of Schistosoma japonicum, and Drosophila melanogaster AAF53019 and AAF53018 and the ortholog from D. pseudoobscura (Dp-22; [ 47]).

The use of surrogate tissue-specific markers can reduce the specificity of the assays and give rise to a clinically unacceptable false-positive rate.

The underestimation of Simple forms reduces the specificity of the test; however, it makes possible to have a high sensibility, reducing the number of false positive cases.

Despite this, in the case of the energy asymmetry method, saturation of signals contributes to reduce the specificity of the parameter and a slight degradation of the resolution can be expected at the boundaries of the DOI range.

Another limiting factor to the use of 18F-FDG for assessment of cardiac sarcoidosis is that both inflammation and myocardial ischemia can increase glucose utilization and can further reduce the specificity of myocardial 18F-FDG uptake.

Large necrotic tissues could have more false-positive uptakes of 11C-MET through variable factors mentioned above than small necrotic tissues, which could reduce the specificity of 11C-MET PET/CT.