Sentence examples for reducing the differentiation from inspiring English sources
Differentiation of embryonic stem cells (ESCs) into specific cell types with minimal risk of teratoma formation could be efficiently directed by first reducing the differentiation potential of ESCs through the generation of clonal, self-renewing lineage-restricted stem cell lines.
For example, in mice models of autoimmune arthritis, GATA-3 expression protects against joint inflammation and destruction by reducing the differentiation of Th17 cells [ 15].
In his presentation last week, Dr. Hern argued that in many parts of the world the increase in human numbers is rapid and uncontrolled, that it invades and destroys habitats, and that by killing off many species it reduces the differentiation of nature.
Burgos et al. ([2004]) reported that allelochemical from rye (Secale cereal L). reduced the differentiation of root cap cells of cucumber (Cucumis sativus L). seedlings.
Thus, inhibition of BMP activity reduces the differentiation of neurons, but does not affect the ability of the neurons to leave the olfactory epithelium.
Our results also show that elevated BMP signals suppress the ability of neurons to leave the olfactory epithelium, while inhibition of BMP activity reduces the differentiation of neurons.
Quantitative-PCR analyses of differentiating ES cells indicate that pharmacological inhibition of BMP signaling during the early critical stage promotes the development of the cardiomyocyte lineage, but reduces the differentiation of endothelial, smooth muscle, and hematopoietic cells.
Both mechanisms reduce the differentiation of osteoclasts and, as a consequence, the amount of bone destruction.
Knockdown of either NFIA or NFIB reduces the differentiation ability of 3T3-L1.
Calvarial-derived osteoblasts from biglycan-deficient mice have reduced the differentiation capability and reduced the responsiveness to BMP-4 (47).
CAFG reduces the differentiation of osteoclasts around the bone surface and in vitro from BMCs comparable to Sham.
