Decreased protein kinase A activity leads to reduced phosphorylation of CREB [ 48], thus reducing the availability of phosphorylated CREB for binding the IL2 promoter.
The available fresh waters are being polluted by anthropogenic factors and are reducing the availability of potable water (Fard et al. 2012).
"The policy-induced budget shortfalls reportedly forced NGOs to cut rural outreach services, reducing the availability of contraceptives in rural areas," Jones wrote.
Savings made by reducing the availability of legal aid for civil cases will be significantly less than half of that predicted by the government, according to a study.
The "iron law" of public health states that reducing the availability of a substance reduces its consumption, which reduces health harms.
In addition, rule changes for export quotas have had the effect of reducing the availability of supplies leaving China.
Reducing the availability of guns to the general population is a more sensible strategy to reduce gun violence.
Congressional leaders were privately relieved that many Republicans had left Washington for the Thanksgiving holiday before Mr. Obama announced plans for his address, reducing the availability of anti-immigration conservatives for cable-television bookers seeking reactions.
As a consequence, wide reporting of the results of this study as if it had been properly executed could have widespread health consequences, like reducing the availability of lower and no-fat foods.
"Reducing the availability of buses will have significant long term impacts socially, environmentally and economically," says Martin Abrams, public transport campaigner at the CBT, "Local and national government need to wake up to that, and quick".
Bankruptcies among small energy-sector companies, which are of limited economic importance themselves, are creating pressures in global banking and reducing the availability of credit to healthy businesses and households that would otherwise be beneficiaries of cheaper oil.
