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Orlistat forms a covalent but reversible bond with the active site serine residue of pancreatic lipase, rendering it unable to hydrolyze dietary fat into free fatty acids, therefore reducing the absorption of dietary fat [14].
Once the defects diffuse to the grain boundaries, they would no longer make a contribution to impurity bands in the Si, thus reducing the absorption of below bandgap radiation.
The SGLT2 inhibitors reduce blood glucose level by reducing the absorption of glucose in the kidneys.
Treatment with pramlintide has been shown to reduce HbA1c by up to -0.6%, as well as prandial insulin requirements [ 20]. α-Glucosidase inhibitors suppress glucose levels by reducing the absorption of carbohydrates from the gastrointestinal tract.
This position statement, however concentrated on the evidence base for the increased elimination of drugs undergoing enterohepatic/enteric circulation, rather than reducing the absorption of sustained-release or modified-release preparations.
Moreover, some studies indicate that chondrosarcoma cells can express multidrug-resistance gene products, such as P-glycoprotein, thereby reducing the absorption of drugs, and giving rise to chemotherapy resistance [ 18, 19].
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Orlistat, sold as Xenical, reduces the absorption of fat from foods.
Antacids, for example, reduce the absorption of the popular antibiotic tetracycline by forming insoluble complexes.
Some horse-feed companies are putting low levels of chemicals in their products that would help reduce the absorption of the mycotoxin.
Soaking breaks down phytic acid and protease inhibitors, naturally occurring substances in nuts, seeds, grains and legumes that protect them until they germinate but can block enzyme function and reduce the absorption of important minerals in your body.
We hypothesized that pantothenic acid reduces the absorption of biotin in lactating dairy cows.
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