Sentence examples for reducing steady from inspiring English sources

Moreover, we show that reducing steady state levels of COMP mRNA alleviates intracellular retention of other extracellular matrix proteins associated with the pseudoachondroplasia cellular pathology.

Second, the half-life of the ubiquitinated intermediates may be quite short, further reducing steady state values of the degradation intermediates.

For example, reducing steady-state oxygen concentration reduced aeration system energy requirements and associated carbon footprint but increased fermenter size and associated cost.

(1) Increasing the ratio of anti- over pro-apoptotic Bcl-2 proteins caused IP3R sensitization, enhancing basal IP3R-mediated Ca2+ leak and reducing steady-state [Ca2+] in the ER.

Interestingly, as stated previously, post-translational degradation of p53 by Mdm2 increases both p yz and p z (degradation rate), while a hypothetical transcriptional suppression would only increase p yz. Hence post-translational suppression of p53 may be more efficient at reducing steady-state error than transcriptional suppression, even though it is less energy efficient.

These GFPs all displayed progenitor-like fluorescence spectra, temperature-sensitive folding, a reduced structural stability and, for the least stable variants, a reduced steady state abundance.

In summary, reduced steady state serum concentrations of progesterone from a CIDR device resulted in continued growth of persistent follicles in cows and heifers compared to a non-manipulated CIDR device.

We tested this hypothesis using RNA interference to reduce steady state levels of COMP mRNA.

In contrast, the integrants containing GA and GB shRNAs that target globular domain sequences did not reduce steady state WT- or MT-COMP mRNA or protein levels (Fig. 2 and data not shown).

We found HRK siRNA treatment significantly reduced steady state mRNA pools of HRK in HCSF treated with C6 ceramide for 6 or 12 hours compared to siNTC transfected cells that had been treated with ceramide (Figure 5A).

Reduced steady state levels of eIF4Gp in the myo1Δ strains are thought to reduce the number of translation initiation events.