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This stringency seems to be reducing over time but remains a problem.
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Encouragingly, reported risky driving behaviours in UK military personnel have reduced over time.
As a consequence, the RNA requirements have reduced over time as technologies have improved.
The most striking observation, however, is that broadly across ages, both incidence and prevalence have reduced over time.
"In terms of the risk factors leading to poor health, 10% of 10 to 24-year-olds are current daily smokers, which has reduced over time, but a health behaviour which hasn't improved is overweight and obesity, with about 30% of young people now overweight or obese".
Of course a public accounts deficit of £175bn-£200bn is very large and has to be greatly reduced over time, but not – repeat, not – by premature swingeing cuts when the recovery, if there is one, is still precarious and when unemployment, bankruptcies and repossessions are still rising.
In contrast, creatinine clearance, as an estimate of glomerular filtration rate, was reduced over time, but not different between experimental groups.
No mechanism for such a bias has been identified, and it is even harder to think of a bias that reduces over time, but bias remains a possibility in principle.
Call abandonment rates were slightly higher than the target of 3%%, but appeared to be reducing over time (5.9 % in 2010 11 to 5%% in 2011 12).
For dementia-related EAs there was a suggestion that inequalities may be reducing over time.
DNA damage was maximal at 1 h, reducing over time (ca. 10 h) in 37 patients.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com