Sentence examples for reducing mutations from inspiring English sources

While telomerase will extend the longevity within our model, we expect it to counteract SITS in reducing mutations at late timepoints.

Our findings highlight the unique features of telomeric versus p53-mediated stress response and suggest that telomere mediated stress-sensing and cell-to-cell heterogeneity are crucial for reducing mutations and extending longevity.

In fact, the MMR plays a key role in maintenance of genomic stability, contributing to tumour suppression by reducing mutations and promoting apoptosis in response to some DNA damage during replication and mitotic recombination processes [ 17, 35].

Also shown is the surface-entropy reducing mutation, E47A in blue or green.

The authors argue that a factor here is the ability of one of the SR proteins to inhibit topo I activity, thus reducing mutation rate.

An additional source of multiple-coding, at least for recognition sites, derives from pressures reducing mutation load at high recombination rates [ 38].

Our finding thus tentatively suggested that TGPAs balance between the deleterious effect of the average mutation and the cost of further reducing mutation rate not by reducing μg but likely by lowering deleteriousness of mutations under stress.

The protein used to co-crystallize the complex contains residues 1 70 and contains the higher-order oligomerization disrupting mutations, L12S and L60R, and the surface-entropy reducing mutation, E47A.

Our first step to reduce mutations was to remove the possibility of cycling-induced errors by conducting all reactions as single-step extensions.

In particular, the shRNA region is separated into two parts at the end of the PCR product, which would reduce mutations during recombination in vivo.

Mutations in both oncogenes and TSGs lead to carcinogenesis, and here, we assume that the mechanisms to reduce mutations have a cost for the organism in terms of decreased birth rate (Moses and Brown 2003).