Sentence examples for reducing lifespan from inspiring English sources

Adipose tissue expansion physiologically occurs during aging and is dramatically accelerated in metabolic diseases reducing lifespan.

Rather than reducing lifespan, haploinsufficiency of Rpd3 results in extended longevity [ 52].

However, these male-derived molecules have a negative effect on female fitness by reducing lifespan [ 7].

We find that the countries that have been the most successful in reducing premature deaths, and consequently in reducing lifespan variation, have consistently been the life expectancy leaders.

Based on additional genetic data, glucose was proposed to activate Git3p, reducing lifespan through the activation of Gα and downstream Ras-cAMP/PKA signaling (Roux et al., 2009).

Adding methionine alone to the dietary restriction condition was necessary and sufficient to increase fecundity as much as did full feeding, but without reducing lifespan.

The end result is a considerably reduced lifespan that is marred by reduced levels of independence, with few novel treatment options available.

Patients endure reduced quality of life (Giraldo et al, 2005) and reduced lifespan compared with healthy controls (vom Dahl et al, 2006a).

In both cases restriction of thermoregulation reduced lifespan.

Transgenic flies engineered to overexpress the human mutant HTT gene display protein aggregation, neurodegeneration, behavioral deficits and a reduced lifespan.

These worms have similar phenotypes to ANCL patients and also to CSP mutants in mice, in terms of reduced lifespan, progressive neuronal dysfunction and neurodegeneration [72].