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Indeed, phosphorylation of Rnd proteins and Rap1A in the cluster of basic amino acids near their C termini is likely to promote membrane extraction by reducing interaction with acidic phospholipids in the membrane.
Release of HMGB1 into the extracellular space is mediated by two mechanisms: 1. Acetylation of many of the lysine residues of HMGB1 that lie in proximity to its two nuclear-localization signals, thus reducing interaction with the nuclear importer protein complex and preventing nuclear re-entry while promoting secretion of HMGB1.
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Lower functional status has been assumed to limit opportunities for social contact by reducing interactions with family and friends outside the home [ 35] and by limiting social activities [ 36].
An A76C variant of hU6 snRNA showed reduced interaction with U4 snRNA, concomitant with reduced spliceosome assembly and low splicing activity (Wolff and Bindereif, 1995).
This was accompanied by a reduced activation of the primary visual cortex, which showed reduced interaction with the amygdala and the insula.
All five variants which showed reduced protein levels in Figure 1A also demonstrated significantly reduced interaction with GCK.
potentially higher anti-inflammatory and anti-pain efficacy; positive action on the bronchial tract (inhibition of bronchoconstriction); reduced adverse effects on the upper GI tract, even with chronic treatment; reduced interaction with ASA.
Reduced interaction with fellow citizens probably only reinforces a person's own beliefs.
Compared to parent GO, intermediate photoproducts exhibited reduced interaction with model cell membranes and altered biomarker responses.
TfL said it would try to reduce the number of lorries on the roads during peak hours to reduce "interaction" with cyclists.
Accept this reduced interaction with your adviser as a fact of life; the ability to work well independently is a key career skill, so develop it.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com