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The current study focused on recently infected individuals and determined exposure to malaria parasites and immune responses in the weeks following a clinical episode, i.e. when there are potentially infectious gametocytes circulating against which transmission reducing immunity can act.
Finally, the shape of the long-term relationship between exposure (EIR) and clinical disease in our model demonstrates that, if multiple effective interventions are implemented, concurrently, with high coverage, it is possible to offset the negative impact of reducing immunity through driving transmission to low levels [14].
65 Two potentially synergistic strategies have been developed for reducing immunity induced by gene therapy for Pompe disease: one is the development of liver-targeted therapies; and the other is immunosuppression/immunomodulation.
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Patients with ADs often have significantly reduced immunity related to chronic immunosuppressive treatments and intrinsic immune suppression in some diseases, such as SLE and T1D.
Rates of illness, reflecting poor nutrition and reduced immunity to disease, are rising alarmingly.
In Deceit and Self-Deception, Trivers synthesises all of his research, including the discovery of a clear correlation between lying and reduced immunity.
These tend to emerge if you are old, infirm, suffer from a chronic illness or respiratory disease, or have a reduced immunity, from HIV or undergoing chemotherapy for instance.
Stress not only increases blood pressure but also messes with your hormones sufficiently to reduce immunity, increase depression and make you fat.
In the recent cases, Aspergillus introduced into a vulnerable part of the body coupled with steroids, which reduce immunity and promote fungus growth, was particularly deadly.
Pregancy reduces immunity in women, to avoid rejection of the developing foetus, and in the later stages the growing foetus can press on the diaphragm reducing lung capacity and increasing the risk of pneumonia.
The flu virus is more likely to get passed from person to person in winter when people have a reduced immunity to illness if they are cold or unwell.
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CEO of Professional Science Editing for Scientists @ prosciediting.com