Exact(11)
The underestimation of Simple forms reduces the specificity of the test; however, it makes possible to have a high sensibility, reducing the number of false positive cases.
Although this probeset could be used to construct a classifier with a reasonably large margin, the presence of a sample of normal tissue with expression close to the cancer group drastically reduces the specificity of a classifier based upon this probeset.
Moreover, absence of a corresponding serum surrogate marker reduces the specificity and sensitivity of these imaging agents.
Inclusion of individuals with autoimmune diabetes and GCK-MODY reduces the specificity of the hs-CRP threshold of 0.4 mg/l to 63%.
This increases the rate of false-positives and thus reduces the specificity of method (1) compared with method (2), which explains the metaregression findings.
This finding may be explained by the fact that treating prevalent cases as incident cases reduces the specificity of the test, which again leads to a misclassified outcome.
Similar(49)
The use of surrogate tissue-specific markers can reduce the specificity of the assays and give rise to a clinically unacceptable false-positive rate.
The authors proposed that AV-45 ROI SUVr included local non-specific white matter uptake, reducing the specificity of the findings compared to PiB in patients.
Figure 3: In silico analyses estimating the rates at which genome-variations reduce the specificity of Cas9.
It is important that gastrin levels be drawn after a period offPPI therapy, as PPIs may elevate gastrin levels and reduce the specificity of the test.
As specific examples, schizophrenia-related personality traits that are unrelated to affective symptoms and performance deficits on tasks of eye tracking and continuous attention are considered for strategies for broadening phenotype characterization without reducing the specificity of affected case identification.
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Justyna Jupowicz-Kozak
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