Sentence examples for reduces responsiveness from inspiring English sources

Aging reduces responsiveness to melatonin treatment and this correlates with reduced functional potency of melatonin receptors.

Such patterns could result from the induction of immunological tolerance [59], which reduces responsiveness to self-tissues or repeatedly encountered, non-pathogenic antigens [60].

Inhibition of JAK3 reduces responsiveness to multiple pro-inflammatory cytokines including IL-2, IL-4, IL-15, and IL-21.

If not, the nocturnal rhythmic burst firing might be a mechanism that filters incoming sensory information and reduces responsiveness to sensory stimuli.

The role of DAPK in the tumorigenesis of gastrointestinal cancer remains unknown, but in malignant lymphoma, loss of DAPK reduces responsiveness to interferon-γ (Katzenellenbogen et al, 1999).

To test whether neuronal IGFBP5 overexpression reduces responsiveness to endogenous IGF1, we immunoprecipitated the IGF1R from the spinal cord and sciatic nerve of 4-day-old Igfbp5 transgenic mice, a time period when endogenous IGF1 levels are high.

Given the ability of IL-4 to regulate Th17 responses (as well as Th1 responses), reduced responsiveness of the IL-4 receptor would be expected to worsen the outcome of RA.

A previous study did not find a generally reduced responsiveness as well because false positive responses and omissions counterbalanced each other [ 27].

Patients may exhibit strikingly abnormal 'sensory behaviours', especially reduced responsiveness to painful stimuli in behavioural variant FTD and exaggerated responses to pain in semantic dementia (Bathgate et al., 2001; Snowden et al., 2001).

Alterations of the biological clock (eg, reduced responsiveness to the stimuli regulating the clock, excessive or insufficient coordination of responses) would disrupt the clock and the corresponding adjustments (Finkel 1976; Timiras 1978; Weinert and Timiras 2003).

Not allowing the use of cluster munitions will increases risk to Coalition forces engaged in combat from enemy counter-fire, reduce responsiveness, decrease the number of different targets that can be attacked within a specified timeframe, and will substantially increase risks of collateral damage by requiring usage of a greater number of large, unitary warheads to accomplish the same mission.