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Both DBT and TBT are much smaller than dexamethasone, which reduces interactions of these organotins with the GR.
One possibility is that CHD2 reduces interactions of non-nucleosomal H3 with naked DNA.
One popular mechanism to enhance the pharmacokinetics of cationic particles is the use of PEGylation; however, nanoparticle passivation with PEG also reduces interactions with cells, thereby limiting the cellular uptake in target tissues.
Different signaling pathways can affect specific interactions; phosphorylation of ERα is necessary for interactions of the receptor with certain coactivators while it reduces interactions with co-repressors (reviewed in [ 25]).
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Inversely, increased porosity based on small pore size reduces interaction between cells and scaffold matrix.
This suggests that phosphorylation of Rnd3 increases its interaction with 14-3-3 14-3-3 14-3-3reduces interaction with the effector proteinsand
Molecular modelling and immunoprecipitation studies showed that the mutation reduces interaction with Cullin 3 (Cul3) in the KLHL9 Cul3 Roc1 E3 ubiquitin ligase complex.
It is important to note that the UCUAN sequence significantly reduces interaction with CFIm in vitro (Venkataraman et al, 2005).
In agreement with a recent study (Lyst et al., 2013), we found that R306C greatly reduces interaction with HDAC3 and Tbl1 of the NCoR corepressor complex.
Lack of group identity not only reduces interaction among landowners, it may also cause the lack of shared cognition about wildfire risk that owners said make cooperation difficult.
In this new position, NADPH has reduced interactions with the inhibitor.
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CEO of Professional Science Editing for Scientists @ prosciediting.com