Sentence examples for reduces activation of from inspiring English sources

As demonstrated in the current study, MRx0004 as a monotherapy can reduce the infiltration of both TH2 and TH17-associated granulocytes, indicating that it potentially reduces activation of both T helper pathways.

Here, we show that inhibition of AMPK by compound C or by shRNA-mediated depletion of LKB1 reduces activation of autophagy by rapamycin in Tsc2-null cells.

PGRN inhibits immune complex-mediated (IC-mediated) neutrophil infiltration in vivo and reduces activation of isolated neutrophils by ICs in vitro (Kessenbrock et al., 2008).

In vitro treatment of primary stellate cells with cyclopamine (Cyc), a pharmacologic inhibitor of the Hh pathway, inhibits activation and slightly decreases cell survival, while a single injection of Cyc into healthy adult mice reduces activation of HSC by more than 50% without producing obvious liver damage.

When you focus your attention on incoming data, such as the feeling of the water on your hands while you wash up, it reduces activation of the narrative circuitry.

In conclusion, we show that the endocannabinoid system is downregulated in chronic pancreatitis and that its augmentation via exogenously administered cannabinoids specifically reduces activation of pancreatic stellate cells.

Inhibition of PKC resulted in reduced Rac activity and reduced activation of the Rac effector PAK.

In ILK-ko mice reduced activation of ser473Akt and reduced crypt proliferation, together with reduced cyclin D1 expression were observed.

Further, modulating the receptor to reduce activation of c-Jun and calpain activity could counteract Aβ activation of these signaling intermediates.

The protective effect of glimepiride was accompanied by reduced binding of PrP82 146 to neurones, reduced activation of cPLA2 and PGE2 production.

Reduced activation of PPARγ due to reduced formation of endogenous ligands for PPARγ most likely explains its role early in human Pca development (8, 27, 28).