Applying this more conservative alpha may have reduced the statistical power of the related test statistic and increased the risk of a Type II error.
This reduced the statistical power of the pressure data to 68%.
The new benchmarks are not prone to the problems associated with using the mean score or the mean rank to evaluate methods, problems which have reduced the statistical power of previous studies.
Compared with Caucasians, the MAFs of these two variants were much rarer in the Chinese populations (0.05 vs. 0.40 for rs10010131 and 0.125 vs. 0.45 for rs8050136) [21], [21], which reduced the statistical power of our samples dramatically.
This may have reduced the statistical power slightly, but it is unlikely that the predictors would have been different if we could have included cases of diabetes treated with diet only.
In our opinion this difference, however, reflects the small number of animals in each experimental group, which reduced the statistical power of the analysis, and the lower effectiveness of minocycline in sensitizing PrP peptides to protease hydrolysis, as shown in cell-free tests [7].
Overall, splitting the data by race of the patient reduced the statistical power of the analysis, but the diversity patterns observed in the combined data sets were largely still apparent in the genotype 1b CA and AA patients and the genotype 1a CA patients.
For example, the genes in the three pathways significantly enriched in response to H1N1 but not H5N1 were, in fact, also up-regulated >1.5-fold in response to H5N1, however the larger size of this geneset (109 versus 64 genes) reduced the statistical significance to a level >0.05.
This will have reduced the statistical power of the regression models.
This may have reduced the statistical power (sensitivity) for detection of virological failure.
Also, separating the pesticides into smaller categories might have reduced the statistical power even further.
