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A maximally effective concentration of the peptide reduced the maximal response to IP3 by 77±7%.
Specifically, out of 92 pools-analyzed, only two had no effect on the maximal conductance, 60 pools reduced the maximal conductance by 16 40% and 30 reduced the maximal conductance by >40%.
Application of glucose, however, induced transport-associated inward Na+ currents and reduced the maximal charge movements (Qmax).
The majority of the remaining FOL pools reduced the maximal conductance of EAG1-expressing patches (Figure 2A), and most of this conductance was recovered with washout.
Diabetes reduced the maximal afterload to which the hearts could pump (105 mmHg versus 150 mmHg).
Isoflurane anaesthesia reduced the maximal β-AR-mediated chronotropic response in non-diabetic animals.
Similar(38)
MARE [ 33, 34] identified 174 maximally informative loci for our data set reducing the maximal total sequence length per specimen from 352,605 bp to 73,925 bp (Additional file 1: Figure S1).
Shorter outer segments and lower chromophore levels reduce the maximal photon catch capacity of cones leading to a reduced light absorption in retinas of R91W Nrl −/− mice in general.
In subsequent weeks, we introduced more difficult checkerboard cues to the animal while reducing the maximal holding period to 900 ms.
Results show that support position optimization can reduce the maximal moment significantly, and deserves more investigation.
The shape of the cells is optimized to reduce the maximal surface electric field and RF loss power.
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