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All variants had reduced specificity for DHB.
Reduced specificity of hippocampal and posterior ventrolateral prefrontal activity during relational retrieval in normal aging.
Including the possible cases improved sensitivity to 92% but reduced specificity to 34% (58 false positives).
Raising the cut-off point to the 10th percentile improved sensitivity to 73%-76 73%-76reduced specificity to 85%-86%.
This reduced specificity is not a serious problem.
Nesting was found necessary for sensitivity anddid not reduce specificity.
Additionally, they show that an induced-fit model reduces specificity.
Cross-reaction reduces specificity and sensitivity of diagnostic tests.
Thus, neither the reduced phoneme specificity in auditory compared with frontal articulatory regions, nor the decrease in phoneme specificity in older compared with young adults, was associated with decreased mean BOLD activity in auditory regions or the older group, respectively.
Figure 3: In silico analyses estimating the rates at which genome-variations reduce the specificity of Cas9.
Yet, such modifications reduce targeting specificity.
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