Sentence examples for reduced sister from inspiring English sources
We show that Saccharomyces cerevisiae Polα/Primase/Ctf4 mutants, proficient in bulk DNA replication, are defective in recombination-mediated damage-bypass by template switching (TS) and have reduced sister chromatid cohesion.
Strikingly, extracts lacking Tipin and And1 also show reduced sister chromatids cohesion.
H3T3 phosphorylation is generated by the kinase Haspin in regions devoid of H3K4 methylation, and its deficiency causes reduced sister chromatid cohesion and defects in metaphase chromosomal misalignment (Dai et al. 2006, 2005; Eswaran et al. 2009).
It could therefore be that reduced sister centromere re-association observed in this experiment was due to defective cohesion establishment in S-phase rathan toan thethe requirement of Eco1 in mitosis.
In PBMC, mistletoe extracts improved DNA repair of damaged cells [ 47] and reduced sister chromatide exchange [ 48].
Our finding that partial deacetylation of Smc3 due to Hos1 overexpression is accompanied by reduced sister chromatid cohesion (Beckouët et al., 2010) is consistent with this.
In essence, the broken social relationship between the proband's mother and her sister has reduced the sister's ability to make informed choices.
They had reduced my sister down to a random mix of letters and numbers.
Simultaneous monitoring the positions of MCAK (Fig. S4), phospho-MCAK, HEC1 and the Aurora B complex (followed by survivin-GFP, Fig. 7A) after SMC2 depletion revealed that the phospho-S95 was markedly reduced between sister kinetochores, while survivin was often stretched along a much longer distance than in normal cells.
Indeed, chromatin immunoprecipitation (ChIP) experiments have suggested that pericentromeric cohesin levels are reduced when sister centromeres are under tension compared to those not under tension (Eckert et al. 2007; Ocampo-Hafalla et al. 2007).
In contrast, DNA FISH targeting the histone gene complex in rapidly cycling early embryos has shown that pairing of this locus remains high through G2 and the early stages of M phase and is reduced as sister chromatids separate during anaphase (Fung et al. 1998).
