He said it had "a de-stressing effect on the skin," meaning that it reduced signs of wear and tear, not a "distressing effect".
Several groups working with mice having the same mutation next established that the drug also reduced signs of premature aging in those rodents.
Tobacco smokers are more susceptible to periodontitis than non-smokers but exhibit reduced signs of clinical inflammation.
Behavioral changes encompassed motor hyperactivity, reduced signs of innate fear/anxiety and associative fear learning, but did not extend to other associative learning paradigms such as learning of spatial cues or aversive tastes.
A ST2 blocking antibody significantly reduced signs of colitis upon injury in mice.
Mice treated with CD97 mAb had reduced signs of arthritis, in a dose-dependent fashion.
Hyperglycemia was also found to be an independent risk factor for electrophysiological [ 38] and clinical [ 10] signs of ICUAW, and increasing insulin dose reduced signs of ICUAW [ 46].
Consistently, DSS-treated St2 /– mice experienced reduced signs of morbidity over the course of the disease when compared with similarly DSS-treated WT animals (figure 4A).
We found reduced signs of pulmonary edema, patchy infiltrates and inflammatory changes in the animals treated with netrin-1 i.v. or netrin-1 inh.
Finally, human cells from AVM patients display reduced signs of lysosomal storage disease upon ectopic overexpression of Vps15 and Vps34 complex.
Furthermore, histology and biochemical analyses of bronchoalveolar lavage specimen showed reduced signs of lung injury and pulmonary inflammation in OLC ventilated animals [ 5].
