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New CARs targeting FRα were developed and showed focused antitumor activity with a reduced potential of toxicity in pre-clinical tumor models (Lanitis et al., 2013).
Urinary N excretion (g/d) decreased with LO supplementation to RCS- and CS-based diets, suggesting reduced potential of N2O emissions.
A decline in manure N excretion and a shift in N excretion from urine to feces were observed when BMCS replaced CCS in the diet, suggesting reduced potential of manure N volatilization.
It was revealed that the γ-Fe2O3 nanoleaves and γ-Fe2O3 nanospheres exhibite the uric acid oxidation at a reduced potential of 303 ± 3 mV with 150% and 80% enhanced electrocatalytic current respectively than GCE.
On initial consideration, the larger EPI population observed in A-V chimeras was unexpected, considering the reduced potential of their component blastomeres.
We suggest that these processes, enhanced variability and stringent molecular quality control, compensate for the apparent reduced potential of complex animals to adapt and evolve.
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These benefits include the following: greatly reduced dependence on nonrenewable fuels and other resources; reduced potential for pollution of industrial processes and products; ability to safely destroy accumulated pollutants for remediation of the environment; improved economics of production; and sustainable production of existing and novel products.
Finally, α6-Cacna1a mice, which lack P/Q-type Ca2+ channels in >75 % of their granule cells and thereby show a reduced potential for excitation of both Purkinje cells and molecular layer interneurons (Galliano et al. 2013a), were obtained by crossing mice carrying a floxed Cacna1a gene with mice having the Cre transgene under control of the GABRA6 promoter (Aller et al. 2003; Todorov et al. 2006).
These results are suggestive of reduced potential for carbon fixation and cellular energy production via carbohydrate metabolism in the zooxanthellae as well as reduced potential for coral skeleton deposition in the RDX exposure.
17 However, unlike any of the conventional botulinum neurotoxin preparations, incobotulinumtoxinA is free from complexing proteins, which may confer clinical benefits in terms of reduced potential for immunostimulating activity.
Reduced expression of transcripts coding photosystem II protein (CAI58622, Additional file 2: Table S6) as well as RT-qPCR validated reductions in pyruvate kinase (XP_001700637), chloroplast light harvesting complex protein (AAW79366) and major facilitator superfamily (AAU87579) in algal symbionts are additional indicators of reduced potential for photosynthesis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com