Sentence examples for reduced perks from inspiring English sources

The company has cut employees' pay and reduced perks like tuition reimbursement and 401(k) matching.

Oh, and they mostly hate that card companies cut many of their credit limits in a time of need and then reduced perks on some cards as if to rub salt in their wounds.

We recently identified IGFBP-2 as a novel regulator of PTEN in breast cancer cells via its interaction with integrin receptors although in those cells the abundance of PTEN protein was reduced (Perks et al, 2007).

ERK is required to potentiate Cyclin D1 expression in these cells, as co-treatment with PD184352, an inhibitor of the Mitogen-activated protein kinase kinase (MEKi), strongly reduced pERK levels in both EtOH- and TAM-treated cells at 12 h (Fig. 1g), but prevented the upregulation of Cyclin D1 exclusively in TAM-treated cells (Fig. 1h).

The data revealed that as early as 2.5 minutes following Kp-10 treatment, significantly reduced pERK levels were detected in the β-arrestin-2 (P<0.05) and Gq/11 (P<0.05) KO cells compared to their corresponding wild-type parental cell lines (Fig. 6B, C).

Treatment with the MEK inhibitor U0126 further reduced pERK levels, and over-expression of KRAS increased pERK levels.

Consistent with this, reduced PERK-P immunostaining after doxycycline treatment in rTg4510 mice has also been reported by others [ 1].

Similar to the co-inhibition experiment in Figure  5A the model predicted reduced pERK levels – however to a much lesser extent than in the co-inhibtion experiment.

Some cell lines, such as WM35 and C8161, demonstrate reduced cell growth in the relative absence of pERK inhibition, whereas others such as 1205Lu and SbCl2 demonstrate reduced pERK levels in the absence of growth inhibition.

While Lvs-siGDNF treatment showed a trend in reduced pERK and ERK immunoreactive cells (Fig. 6a– j), Western blot analysis showed that Lvs-siGDNF treatment significantly decreased the ratio of pERK/ERK in spinal cord segment L4 6 compared to the vehicle (NC -treated group (8.02 ± 2.41 iNC -treatedreated groups; 0.94 ± 0.48.02 Lvs-siGDNF treated group; P = 0.044) (Fig. 6k).

Interestingly, treatment of MM cells with VPA increased the expression of pERK-1 and reduced pERK-2 levels; in this regard, although the reason for the preferential phosphorylation of ERK-1 in VPA-treated myeloma cells was not investigated, the underlying mechanism might be explained by loss of competition between ERKs for their binding/activation by mitogen-activated protein kinases [ 23].