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While individual enzymes within each group (AAADs, SDCs, and GDCs) maintain high identity (typically greater than 50%), enzymes between these related groups maintain significantly reduced identity (typically lower than 15%).
While individual enzymes within each group (AAADs and SDCs) retain high sequence identity (typically greater than 50%), enzymes between these related groups maintain significantly reduced identity (typically lower than 15%).
Compared to genome-wide data, human and mouse ortholog pairs of maternally expressed genes are less conserved in terms of cDNA identity (p < 0.05) and the encoded proteins show a trend towards reduced identity (p < 0.06; Table 1, data for individual imprinted genes are given in additional file 1).
Subsequently, putative genes without any orthologous relation due to reduced identity percentage were integrated in a pre-existing orthologue group if they were flanked by orthologous genes showing gene order conservation (microsynteny).
This reduced identity is particularly pronounced in clade 2, where it ranges from 28 to 57% as a result of a large number of substitutions (e.g. PeMADS5 and SpodoDEF2) or early stop codons (e.g. OMADS3 and GogalDEF2) that eliminated the positions encoding for the otherwise highly conserved C-terminal 'PI-derived' and 'paleoAP3' motifs (Additional file 2).
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Teenagers may also be out of luck, since facial recognition (now used by D.M.V.'s in four states) is expected to greatly reduce identity fraud and with it a kid's ability to procure a fake ID by posing as an older sibling.
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CRaNHR shares only aggregated data (cell size >5) with NOSM personnel or other stakeholders and researchers, and follows other Statistics Canada guidelines to reduce identity, attribute or residual disclosure.
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