Sentence examples for reduced global level from inspiring English sources

A compromise in PcG-associated HMTase activity was also observed in Asxl2−/− hearts, which exhibit reduced global level of H3K27me3 (Fig. 5F).

Repeated cocaine administration reduced global levels of H3K9 dimethylation in the nucleus accumbens.

Results showed that 1.3 μM BIX-01294 markedly reduced global levels of H3K9me2 with almost no cellular toxicity.

Western blotting also showed that SETD2 knockdown significantly reduced global levels of H3K36me3, confirming SETD2 as the major H3K36me3 methyltransferase in human cells.

In cell-based assays, EPZ004777 reduced global levels of H3K79me2 (dimethylation of H3K79) in a number of leukemia cell lines and did not significantly reduce any other histone marks.

EPZ-5676 reduced global levels of H3K79me2 in several cell lines including MV4-11 (a MLL-AF4 expressing acute leukemia cell line) but did not significantly change other histone methylation marks.

Reduced global levels of H3K9me3 and histone 3 acetylation have been reported in lupus CD4+ T cells, and differences in the activity of histone acetyl-transferases have been observed in lupus CD4+ T cells [ 72]. Sullivan and colleagues [ 81] initially reported variability in histone 4 acetylation at the tumor necrosis factor alpha (TNF-α) locus in lupus monocytes.

In fact, the treaty is not expected to reduce global levels of mercury in fish and seafood at all.

Production of 2HG by mutant IDH1 expression was sufficient to reduce global levels of DNA hydroxymethylation in prostate epithelial cells.

Our results suggest that BIX-01294 may reduce global levels of H3K9me2 and affect epigenetic modifications of Snrpn in MEFs.

These results suggest that BIX-01294 may reduce global levels of H3K9me2 and affect epigenetic modifications of Snrpn in MEFs.