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Minimizing attrition is a key objective in longitudinal research, with possible consequences being additional bias and reduced generalizability.
The procedure of following up both randomized and nonrandomized patients is recommended when there is concern about selective participation and reduced generalizability.
Even so, we cannot rule out the potential for selection bias and reduced generalizability.
Hence, this might have led to selection bias in our study, and led to reduced generalizability of our findings.
A third limitation is that this study was performed mostly at one institute in the Netherlands which could have reduced generalizability regarding setting and time.
First, offering screening in only three general practices may have reduced generalizability of the findings; participation rates of screening differed significantly between these practices.
Similar(53)
These studies, however, are rare, difficult and expensive to implement, and prone to biases that could reduce generalizability of results.
This reduces generalizability of the study results to comparable countries only.
All participants were Caucasian, which may reduce generalizability to non-white groups.
As mentioned above, the small survey sample may reduce generalizability of the results.
In these observer-blinded studies, only two experienced observers assessed all scans, potentially reducing generalizability of their findings.
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