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Overall, this work shows that RSM can be effectively used to elucidate interactions among multiple engine operating parameters with reduced experimentation to optimize complex dual-fuel RCCI combustion modes.
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The model reduces experimentation significantly; in principle, it requires only a single non-reacting experiment to obtain the macromixing parameter and a single reacting experiment to obtain the micromixing parameter.
Any efforts to bring an end to tobacco use for good must include reducing experimentation and tobacco use among teenagers and pre-teens.
22 Perceptions that tobacco is difficult to access and consume are associated with reduced smoking experimentation 16 and decreased opportunities for social exchange.
Design of experiments is targeted to generate informative data and to reduce the experimentation effort as much as possible.
1 13 16 40 Reducing smoking experimentation and subsequent uptake among adolescents is crucial to realisation of tobacco endgame strategies and requires reductions in tobacco supply.
In parallel, the scientific community should improve standardisation of fibrosis models to increase the comparability of data between different laboratories with the aim of reducing animal experimentation.
With the changes introduced to laboratory classes worldwide, to reduce animal experimentation, these classes were replaced by class demonstrations and then by a video showing an experiment conducted in a class.
These interventions appear to have been effective in reducing first experimentation with smoking among the younger age groups but not among the 15-year-olds and to have failed to reduce the prevalence of current smokers or daily smokers which has remained substantially unchanged over time.
Another study concluded that copyrighting new gene sequences sharply reduced scientists' subsequent experimentation with the decoded genes, even if they were later placed in the public domain.
The development of certain heuristics for prioritizing the likelihood of chemical formulae reduces the number of possible chemical formulae, but leaves some ambiguity that can be reduced through additional experimentation [ 11, 12].
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