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Compared to natural cyclopamine, these cyclopamine isomers have a significantly reduced effect on the ciliary transport of the Hh receptor smoothened, and reduced inhibition on the Hedgehog signaling pathway.
Thus the aims of this study were to determine whether the beneficial effect of laterally wedged insoles on the adduction moment declined over one month of wear, and whether higher reported use was associated with a reduced effect on the adduction moment at one month.
This study aimed to determine whether the effect of laterally wedged insoles on the adduction moment in knee osteoarthritis (OA) declined after one month of wear, and whether higher reported use of insoles was associated with a reduced effect on the adduction moment at one month.
"As a European view, the first reaction was 'if we have to move it, January/February is the best option', because it will have a reduced effect on the European game because many of the leagues are on winter breaks; it would make things a a little bit more logical," he said.
Site-level posterior distributions shrunk towards the regional mean, where the extreme high- and low-value effect sizes had a reduced effect on the overall estimates.
Instead the search should focus on compounds that show a reduced effect on the expression of these IR genes.
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The trans-eQTLs have been observed less frequently than cis-eQTLs in humans and tend to display reduced effects on the regulated gene (Schadt et al. 2008).
It has a coefficient value of -10.436 which has a reducing effect on the constant.
The coarse basalt aggregate has limited reducing effect on the mechanical strength of UHPC.
However, the plant may be a potential hypoglycemic or anti-diabetic agent, since it had a reducing effect on the plasma glucose levels.
Raising the allocation of resources to programme administration has a reducing effect on the unemployment rate, either directly or through its interaction with policy variables.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com